Major congenital malformations of foetus: a bane in pregnancy
نویسندگان
چکیده
منابع مشابه
Valproic acid monotherapy in pregnancy and major congenital malformations.
BACKGROUND The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but data on the risks of other congenital malformations are limited. METHODS We first combined data from eight published cohort studies (1565 pregnancies in which the women were exposed to valproic acid, among which 118 major malformations were observed) and identified...
متن کاملCongenital malformations and environmental influences in pregnancy.
Most human congenital malformations are believed to be due to the interaction of both genetic and environmental influences. Neither retrospective enquiry (e.g., Record, 1958) nor prospective study (e.g., McDonald, 1961) has yet been of much value in uncovering the environmental factors responsible and, with the exception of maternal rubella infection and a small number of drugs (notably thalido...
متن کاملAntiepileptic drugs prescribed in pregnancy and prevalence of major congenital malformations: comparative prevalence studies
OBJECTIVE The aim of this study was to examine the prevalence of major congenital malformations associated with antiepileptic drug (AED) treatment in pregnancy. PATIENTS AND METHODS Using data from The Health Improvement Network, we identified women who have given live birth and their offspring. Four subgroups were selected based on the AED treatment in early pregnancy, valproate, carbamazepi...
متن کاملHormonal pregnancy tests and congenital malformations.
I have read with interest Dr. D.T. Janerich's article (April 23, p. 1058) confirming the teratological effect of hormonal pregnancy tests and other exogenous sex hormone preparations in relation to congenital heart diseases. The discovery of the teratological effect of hormonal pregnancy tests emerged from my studies into central nervous system malformations in 1967. In this and in further pu...
متن کاملCongenital multi-organ malformations in a Holstein calf
A 5-day-old female Holstein calf was necropsied because of lethargy, recumbency and anorexia. At necropsy, multiple gross defects were evident in several organs, including unclosed sutures of skull bones, asymmetrical orbits, doming of the skull bones, hydrocephalus, hydranencephaly, cleft palate, brachygnathia, ventricular septal defect, mitral valve dysplasia and rudimentary lungs. On microsc...
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ژورنال
عنوان ژورنال: International Journal of Reproduction, Contraception, Obstetrics and Gynecology
سال: 2020
ISSN: 2320-1789,2320-1770
DOI: 10.18203/2320-1770.ijrcog20204803